#196: Research on myelin repair. Interview with Dr. Markley Silva Oliveira Junior on the effect of corticosteroid medrysone

Dr. Markley Silva Oliveira, Jr. has done research on astrocytes
and how they can contribute to better myelin repair using
Medrysone.


Here you can find the written blog article to read through:
https://ms-perspektive.de/196-myelin-repair-markley















Episode 196 is about an exciting
research work on myelin repair in the
progressive course of MS with the help
of astrocyte cells that contribute to
it under administration of Medrysone, a
coricosteroid.


My interview guest is Dr. Markley Silva
Oliveira Junior, who wrote his doctoral
thesis on this topic at Heinrich Heine
University in Düsseldorf. It didn’t
stop at writing alone, though; Markley
did a lot of experimentation and found
amazing things about astrocytes, whose
impact used to be viewed rather
negatively, but which make a crucial
contribution to repair.


And since Medrysone is already an
approved drug in the field of
ophthalmology, it could go faster with
the approval, if the successful results
from animal experiments, are equally
good for humans.


The podcast and blog post are
also available in German
translation.





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Table of Contents





Introduction of Dr. Markley
Silva Oliveira-Junior




Mechanism of myelin repair
in MS-patients




The effect of
corticosteroid medrysone on the
myelin repair in
MS-patients




Farewell








Introduction of Dr. Markley Silva
Oliveira-Junior






Hi everyone. Just glad to be here in
invitation from Nele, many thanks for
having me.  Well, I’m a very
honored Brazilian guy, neuroscientist,
married, I love a good hiking,
travelling, good food (quite spoiled I
am for being Brazilian, but France and
Italy have my heart on that) and of
course hangout with my friends and
family.









How and where can interested people
follow the most recent research
activities?






In my
LinkedIn I’m always
sharing things that I found
interesting about research.
Sometimes, I do my own posts,
otherwise I’m sharing what I
think is interesting there. For
me, if you’re interested in MS,
for example, the MS
UK portal is one of
the key ones to be looking into,
if you are a layperson or if you
are an expert. You can get things
regarding to that. As a
scientist, my key portal to be
looking into is
basically PubMed,
but if you want to know more
about what I’m doing, my LinkedIn
is actually the best
recommendation that I can do to
follow what I’ve been working
with. For example, I’m planning
to do a post next week, where I
will address a little bit more
what I’ve been working with some
clients, regarding Alzheimer’s
and also MS. I will not tell
everything, of course, because of
the patent issue and we are
planning inside our company to
start to share a little bit more
of what we’ve been working,
regarding health promotion, which
is basically what we scientists
are here to do. Even though we
are in academia or not, we are
here to promote health.






Is there anything else you would like
to share with the listeners?






One thing in particular is that I
love science communication, and I
think this is really necessary to
make science be better for
everyone. And podcasts like the
one that you have are actually
giving people the opportunity to
talk, is giving voice to express
what they think about it. Every
time that you listen, you will
filter… you need to put something
out of your mouth, out off your
chest, do it kindly but always
think about the audience. We, as
scientists, we have changed the
way that we talk about science
over the years and I think that
one of the things that makes me
happy to be a scientist is how
important science communication
is today, so we can give people
the right to know. I think this
is one of the most important
things in science communication.
It’s giving the people the right
to know. Because we, as
scientists, back in years we were
thought we were crazy guys, with
“Eureka” all the time, living in
a dark place, not sharing or not
knowing how to explain what we do
to people and this was actually
what media put out about what
being a scientist was. And we’re
not really like this. We’re
normal people, who like to go out
… I think one of the things that
your podcast gives opportunities
to scientists is to talk more in
a simple way about their work,
about their research. Science
communication is for this, it is
for everyone.







---







Many thanks to Markley for the
insight into the exciting
research around astrocytes, their
role in demyelination, and how to
possibly stimulate them in the
human brain using Medrysone.


Make the most of your life and
become or remain a well-informed
patient,
Nele


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