Einfluss der Mutterschutzimpfung gegen Mycoplasma hyopneumoniae auf den Impfschutz der Ferkel

Enzootic Pneumonia primarily caused by Mycoplasma hyopneumoniae is
a reason for high economic losses in pig production worldwide. In
most herds, the vaccination of piglets with one-shot or two-shot
Mycoplasma hyopneumoniae vaccines is used as a prophylaxis against
enzootic pneumonia. The influence of maternal antibodies on the
effect of the vaccines is discussed controversially. The objective
of this study was to evaluate the effect of the
StellamuneMycoplasma (Two-Shot) and StellamuneOne (One-Shot)
(Pfizer) against Mycoplasma hyopneumoniae on the performance of the
piglets and to evaluate the influence of maternal antibodies.
Furthermore sow colostrum was tested with an ELISA (HerdCheck
M.hyo, IDEXX) as an alternative test for the detection of
Mycoplasma hyopneumoniae antibodies. The present study was done in
a herd of sows with a growing unit, which was followed up on a
fattening farm. The trials were done from December 2002 to June
2004. In the present study 254 sows and 423 piglets were included.
These were divided into five treatment groups: group 1: vaccinated
sows/ one-shot-vaccinated piglets; group 2: vaccinated
sows/two-shot-vaccinated piglets; group 3: non vaccinated sows/
one-shot-vaccinated piglets; group 4: non-vaccinated sows/
two-shot-vaccinated piglets; group 5: non-vaccinated sows/
non-vaccinated piglets. After vaccination of 148 sows 147 of them
had seroconverted three weeks a.p.. Piglet antibody concentrations
from the vaccinated and non vaccinated sows one week p.n. showed
that the sow vaccination induces a high concentration of maternal
antibodies in piglets. Sow vaccination did not interfere with the
humeral antibody response after piglet vaccination. At the age of
20 weeks no significant differences in humeral immune response were
found in groups of vaccinated piglets. The non vaccinated piglet
group showed significantly lower values than the four vaccinated
piglet groups. All vaccinated piglet groups showed significantly
better lungscores than the unvaccinated group. A significant
difference was also found between the groups with
one-shot-vaccinated piglets. he group of non-vaccinated sows showed
a significantly better lungscore. This could be an indication for
the interference of high amounts of maternal antibodies on the
effect of the StellamuneOne vaccine. In 105-day-old pigs no
significant differences were evaluated on the average daily weight
gain. The different vaccination schemes had no influence on the
body weight until the pre-fattening period. Examing sow colostrums
at a dilution of 1:10 with an ELISA had a sensitivity of 85% and a
specificity of 55%, seemed to be an appropriate method to exclude
Mycoplasma hyopneumoniae infections in the herd. In conclusion the
vaccination of piglets in this herd in this herd with the
StellamuneMycoplasma and StellamuneOne against Mycoplasma
hyopneumoniae improved the pulmonary health and had no negative
influence on the production of humeral antibody values.