Investigations into idiopathic hypertriglyceridemia in the Miniature Schnauzer in North America

Idiopathic hypertriglyceridemia has been reported in Miniature
Schnauzers. However, studies investigating the prevalence of this
disorder in a large population of Miniature Schnauzers are lacking.
192 healthy Miniature Schnauzers and 38 healthy dogs of other
breeds (control dogs) were enrolled in this study. Serum
triglyceride and cholesterol concentrations were measured and
statistically compared between the Miniature Schnauzers and the
control group. Dogs were categorized based on their age, and median
serum triglyceride concentrations were compared among different age
groups. A total of 63 (32.8%) of the 192 Miniature Schnauzers had
serum triglyceride concentrations above the upper limit of the
reference range. In contrast, of the 38 control dogs, only 2 (5.3%)
had serum triglyceride concentrations above the upper limit of the
reference range. The median serum triglyceride concentration in
Miniature Schnauzers was 73.5 mg/dL, which was significantly higher
compared to that of the control group (median: 55 mg/dL; p=0.0005).
Serum cholesterol concentration was above the upper limit of the
reference range in 9 (9.0%) of 100 Miniature Schnauzers and in 2
(5.3%) of the control dogs. Mean serum cholesterol concentrations
were not significantly different between the 2 groups (p=0.1374).
Median serum triglyceride concentrations in Miniature Schnauzers
increased significantly with age (p