Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation

Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation

Beschreibung

vor 20 Jahren
This examination is an approach of the allergic late phase reaction
via quality of life, acoustic rhinometry, and determination of ECP,
IL-5, IL-8, MCP-1, MCP-3, RANTES, sVCAM-1, and LTC4 in nasal
secretions. It describes and discusses changes in subjective and
objective parameters over a time period of eight hours following
nasal allergen application. Data obtained from a clinical and an
experimental part is analyzed and statistically compared in
reference to the existence of an early and late phase allergic
reaction. Results are discussed under consideration of a possible
neurological participation in the occurrence and persistence of the
allergic inflammatory process.

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