Effect of pancreatic and/or renal transplantation on diabetic autonomic neuropathy

Thirty-nine Type 1 (insulin-dependent) diabetic patients were
studied prospectively after simultaneous pancreas and kidney (n=26)
and kidney grafting alone (n=13) by measuring heart rate variation
during various manoeuvers and answering a standardized
questionnaire every 6 to 12 months post-transplant. While age,
duration of diabetes, and serum creatinine (168.1±35.4 vs
132.7±17.7 mgrmol/l) were comparable, haemoglobin A1 levels were
significantly lower (6.6±0.2 vs 8.5±0.3%; p