Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis

The role of the atrial natriuretic factor and of the main
counteracting sodium-retaining principle, the renin-aldosterone
system, in acute volume regulation of cirrhosis of the liver has
been investigated. Central volume stimulation was achieved in 21
patients with cirrhosis, 11 without and 10 with ascites, and 25
healthy controls by 1-hr head-out water immersion. Immersion
prompted a highly significant (p