Investigation of marmoset hybrids (Cebuella pygmaea x Callithrix jacchus) and related Callitrichinae (Platyrrhini) by cross-species chromosome painting and comparative genomic hybridization

We report on the cytogenetics of twin offspring from an
interspecies cross in marmosets (Callitrichinae, Platyrrhini),
resulting from a pairing between a female Common marmoset
(Callithrix jacchus, 2n = 46) and a male Pygmy marmoset (Cebuella
pygmaea, 2n = 44). We analyzed their karyotypes by
multi-directional chromosome painting employing human, Saguinus
oedipus and Lagothrix lagothricha chromosome-specific probes. Both
hybrid individuals had a karyotype with a diploid chromosome number
of 2n = 45. As a complementary tool, interspecies comparative
genomic hybridization (iCGH) was performed in order to screen for
genomic imbalances between the hybrids and their parental species,
and between Callithrix argentata and S. oedipus, respectively.
Copyright (C) 2005 S. Karger AG, Basel.