Carbamazepine-responsive paroxysmal nausea and vomiting in a patient with meningeal carcinomatosis

In neurology, paroxysmal syndromes are well-known, eg, as
manifestations of multiple sclerosis. We report a patient with
meningeal carcinomatosis, who presented with therapyrefractory
nausea and vomiting. The clinical suspicion of a paroxysmal
syndrome prompted a trial of carbamazepine, which resulted in
complete cessation of the symptoms. In cancer patients with central
nervous system (CNS) involvement and therapy-refractory symptoms
with sudden onset, carbamazepine treatment should be considered.