Comparative chromosome painting discloses homologous Segments in distantly related mammals
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vor 30 Jahren
Comparative chromosome painting, termed ZOO-FISH, using DNA
libraries from flow sorted human chromosomes 1,16,17 and X, and
mouse chromosome 11 discloses the presence of syntenic groups in
distantly related mammalian Orders ranging from primates (Homo
sapiens), rodents (Mus musculus), even-toed ungulates (Muntiacus
muntjak vaginalis and Muntiacus reevesi) and whales (Balaenoptera
physalus). These mammalian Orders have evolved separately for 55-80
million years (Myr). We conclude that ZOO-FISH can be used to
generate comparative chromosome maps of a large number of mammalian
species.
libraries from flow sorted human chromosomes 1,16,17 and X, and
mouse chromosome 11 discloses the presence of syntenic groups in
distantly related mammalian Orders ranging from primates (Homo
sapiens), rodents (Mus musculus), even-toed ungulates (Muntiacus
muntjak vaginalis and Muntiacus reevesi) and whales (Balaenoptera
physalus). These mammalian Orders have evolved separately for 55-80
million years (Myr). We conclude that ZOO-FISH can be used to
generate comparative chromosome maps of a large number of mammalian
species.
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