Implementation of Novel Biomarkers in the Diagnosis, Prognosis, and Management of Acute Kidney Injury: Executive Summary from the Tenth Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)

Detection of acute kidney injury is undergoing a dynamic revolution
ofbiomarker technology allowing greater, earlier, and more
accuratedetermination of diagnosis, prognosis, and with powerful
implication formanagement. Biomarkers can be broadly considered as
any measurablebiologic entity or process that allows
differentiation between normalfunction and injury or disease. The
ADQI (Acute Dialysis QualityInitiative) had its Ninth Consensus
Conference dedicated to synthesisand formulation of the existing
literature on biomarkers for thedetection of acute kidney injury in
a variety of settings. In the papersthat accompany this summary,
ADQI workgroups fully develop key conceptsfrom a summary of the
literature in the domains of early diagnosis,differential
diagnosis, prognosis and management, and concurrentphysiologic and
imaging measures.