Long-Term Changes of Central Ocular Motor Signs in Patients with Vestibular Migraine

Background: A high percentage of patients with vestibular migraine
(VM)were reported to have central ocular motor dysfunctions (COMD)
in thesymptom-free interval. Since VM is a chronic disorder, it is
of interestif COMD worsen over time. Methods: Thirty VM patients
and 11 controlpatients participated in an 8-year-long observational
study withfollow-up. All patients underwent standardized
neuro-ophthalmologicaland neuro-otological examinations at the
initial presentation and atfollow-up. The primary outcome measure
was change in COMD at follow-up.Results: In general, COMD in the
symptom-free interval were subtle,consisting of a saccadic
horizontal and/or vertical pursuit.