Solltest Du Vitamin D einnehmen? Das sagt die Wissenschaft (#494)

Was man teilweise über Vitamin D hört, klingt fast zu schön, um
wahr zu sein.


Andererseits deuten hunderte verschiedener Forschungsarbeiten
darauf hin, dass Vitamin D zur Vorbeugung einer Reihe von
Krankheiten beitragen kann – darunter Osteoporose, Depression,
Autoimmun- und Herz-Kreislauf-Erkrankungen.


Ärzte empfehlen es. Gesundheits- und Fitnesspodcaster sprechen
darüber. Vielleicht geht Dir sogar Deine Lieblingstante damit auf
die Nerven.


Bei all dem Hype ist die Frage berechtigt: "Solltest Du Vitamin D
einnehmen?" Hier sind die Antworten – und die neuesten Fakten
über ein faszinierendes Vitamin, das ein wahrer
Verwandlungskünstler ist.


____________


*WERBUNG: KoRoDrogerie.de: 5% Ermäßigung auf
alles mit dem Code „FMM“ beim Checkout.


____________


Ressourcen zur Folge:


Literatur:


Ratgeber Nahrungsergänzung – Mark Maslow (kostenlos auf
MarathonFitness)

Blut: Die Geheimnisse unseres flüssigen Organs* – Ulrich
Strunz (Heyne)

Vitamin D* – Uwe Gröber, Michael F. Holick (Wissenschaftl.
Verlagsgesellschaft)



Blutuntersuchung (Selbsttest):


Vitamin D Test* von Medivere



Präparate:


D-Form 2.000 K2+* von FormMed

D-Form 2.000 K2+ vegan* von FormMed



____________


️ Kostenloser Newsletter: Schließ Dich den über
30.000 Dranbleibern an, die über den #DRNBLBR Newsletter
wöchentlich neue Ideen tanken, die easy fit machen:
www.dranbleiber.com.


____________


Fachliteratur:


Schottker B, Haug U, Schomburg L, et al. Strong associations
of 25-hydroxyvitamin D concentrations with all-cause,
cardiovascular, cancer, and respiratory disease mortality in a
large cohort study.  Am J Clin Nutr. 2013 Apr;97(4):782-93.


Kimball, Samantha M., and Michael F. Holick. 2020. “Official
Recommendations for Vitamin D through the Life Stages in
Developed Countries.” European Journal of Clinical Nutrition 74
(11): 1514–18.


Grammatikopoulou, Maria G., Konstantinos Gkiouras, Meletios P.
Nigdelis, Dimitrios P. Bogdanos, and Dimitrios G. Goulis. 2020.
“Efficacy of Vitamin D3 Buccal Spray Supplementation Compared to
Other Delivery Methods: A Systematic Review of Superiority
Randomized Controlled Trials.” Nutrients 12 (3).
https://doi.org/10.3390/nu12030691.


Tripkovic, Laura, Helen Lambert, Kathryn Hart, Colin P. Smith,
Giselda Bucca, Simon Penson, Gemma Chope, et al. 2012.
“Comparison of Vitamin D2 and Vitamin D3 Supplementation in
Raising Serum 25-Hydroxyvitamin D Status: A Systematic Review and
Meta-Analysis.” The American Journal of Clinical Nutrition 95
(6): 1357–64.


Logan, Victoria F., Andrew R. Gray, Meredith C. Peddie, Michelle
J. Harper, and Lisa A. Houghton. 2013. “Long-Term Vitamin D3
Supplementation Is More Effective than Vitamin D2 in Maintaining
Serum 25-Hydroxyvitamin D Status over the Winter Months.” The
British Journal of Nutrition 109 (6): 1082–88.


Vieth, Reinhold. 2020. “Vitamin D Supplementation:
Cholecalciferol, Calcifediol, and Calcitriol.” European Journal
of Clinical Nutrition 74 (11): 1493–97.6


Khan, Safi U., Muhammad U. Khan, Haris Riaz, Shahul Valavoor, Di
Zhao, Lauren Vaughan, Victor Okunrintemi, et al. 2019. “Effects
of Nutritional Supplements and Dietary Interventions on
Cardiovascular Outcomes: An Umbrella Review and Evidence Map.”
Annals of Internal Medicine 171 (3): 190–98.


Michos, Erin D., Miguel Cainzos-Achirica, Amir S. Heravi, and
Lawrence J. Appel. 2021. “Vitamin D, Calcium Supplements, and
Implications for Cardiovascular Health: JACC Focus Seminar.”
Journal of the American College of Cardiology 77 (4): 437–49.


Ushiroyama, Takahisa, Atushi Ikeda, and Minoru Ueki. 2002.
“Effect of Continuous Combined Therapy with Vitamin K(2) and
Vitamin D(3) on Bone Mineral Density and Coagulofibrinolysis
Function in Postmenopausal Women.”Maturitas 41 (3): 211–21.


Shea, M. Kyla, and Rachel M. Holden. 2012. “Vitamin K Status and
Vascular Calcification: Evidence from Observational and Clinical
Studies.” Advances in Nutrition 3 (2): 158–65.


Shea, M. Kyla, Christopher J. O’Donnell, Udo Hoffmann, Gerard E.
Dallal, Bess Dawson-Hughes, José M. Ordovas, Paul A. Price,
Matthew K. Williamson, and Sarah L. Booth. 2009. “Vitamin K
Supplementation and Progression of Coronary Artery Calcium in
Older Men and Women.” The American Journal of Clinical Nutrition
89 (6): 1799–1807.


Masterjohn, Christopher. 2007. “Vitamin D Toxicity Redefined:
Vitamin K and the Molecular Mechanism.” Medical Hypotheses 68
(5): 1026–34.


Deng, Xinqing, Yiqing Song, Joann E. Manson, Lisa B. Signorello,
Shumin M. Zhang, Martha J. Shrubsole, Reid M. Ness, Douglas L.
Seidner, and Qi Dai. 2013. “Magnesium, Vitamin D Status and
Mortality: Results from US National Health and Nutrition
Examination Survey (NHANES) 2001 to 2006 and NHANES III.”BMC
Medicine 11 (August): 187.


Uwitonze, Anne Marie, and Mohammed S. Razzaque. 2018. “Role of
Magnesium in Vitamin D Activation and Function.” The Journal of
the American Osteopathic Association 118 (3): 181–89.


Johansson, S., and H. Melhus. 2001. “Vitamin A Antagonizes
Calcium Response to Vitamin D in Man.” Journal of Bone and
Mineral Research: The Official Journal of the American Society
for Bone and Mineral Research 16 (10): 1899–1905.


Institute of Medicine (US) Committee to Review Dietary Reference
Intakes for Vitamin D and Calcium. 2011. Dietary Reference
Intakes for Calcium and Vitamin D. Edited by A. Catharine Ross,
Christine L. Taylor, Ann L. Yaktine, and Heather B. Del Valle.
Washington (DC): National Academies Press (US).
German Nutrition Society. "New reference values for vitamin D."
Ann Nutr Metab. 2012;60(4):241-246. doi:10.1159/000337547

Holick, Michael F., Neil C. Binkley, Heike A. Bischoff-Ferrari,
Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Hassan
Murad, Connie M. Weaver, and Endocrine Society. 2011.
“Evaluation, Treatment, and Prevention of Vitamin D Deficiency:
An Endocrine Society Clinical Practice Guideline.” The Journal of
Clinical Endocrinology and Metabolism 96 (7): 1911–30.
Robert Koch Institute. 2019. "Wie ist die Vitamin-D-Versorgung
in Deutschland?"
https://www.rki.de/SharedDocs/FAQ/Vitamin_D/FAQ08.html, Aufruf:
21.10.2024.

Amrein, Karin, Mario Scherkl, Magdalena Hoffmann, Stefan
Neuwersch-Sommeregger, Markus Köstenberger, Adelina Tmava
Berisha, Gennaro Martucci, Stefan Pilz, and Oliver Malle. 2020.
“Vitamin D Deficiency 2.0: An Update on the Current Status
Worldwide.” European Journal of Clinical Nutrition 74 (11):
1498–1513.


Dierkes, Jutta. 2019. "Vitamin D – eine Übersicht über die
Versorgungslage und Gesundheitseffekte" Trillium Diagnostik,
Labormanagement Heft 3/2019.


Parva, Naveen R., Satish Tadepalli, Pratiksha Singh, Andrew Qian,
Rajat Joshi, Hyndavi Kandala, Vinod K. Nookala, and Pramil
Cheriyath. 2018. “Prevalence of Vitamin D Deficiency and
Associated Risk Factors in the US Population (2011-2012).” Cureus
10 (6): e2741.


Cashman, Kevin D., Tony Sheehy, and Colette M. O’Neill. 2019. “Is
Vitamin D Deficiency a Public Health Concern for Low Middle
Income Countries? A Systematic Literature Review.” European
Journal of Nutrition 58 (1): 433–53.


Wacker, Matthias, and Michael F. Holick. 2013. “Sunlight and
Vitamin D: A Global Perspective for Health.”
Dermato-Endocrinology 5 (1): 51–108.


Forrest, KY, Stuhldreher, WL. Prevalence and correlates of
vitamin D deficiency in US adults.  Nutr Res. 2011
Jan;31(1):48-54.


Chalcraft, Jenna R., Linda M. Cardinal, Perry J. Wechsler, Bruce
W. Hollis, Kenneth G. Gerow, Brenda M. Alexander, Jill F. Keith,
and D. Enette Larson-Meyer. 2020. “Vitamin D Synthesis Following
a Single Bout of Sun Exposure in Older and Younger Men and
Women.” Nutrients 12 (8). https://doi.org/10.3390/nu12082237.


Silva, Mariana Costa, and Tania Weber Furlanetto. 2018.
“Intestinal Absorption of Vitamin D: A Systematic Review.”
Nutrition Reviews 76 (1): 60–76.


Institute of Medicine, Food and Nutrition Board, and Committee to
Review Dietary Reference Intakes for Vitamin D and Calcium. 2011.
Dietary Reference Intakes for Calcium and Vitamin D. National
Academies Press.


Wang, Hanmin, Weiwen Chen, Dongqing Li, Xiaoe Yin, Xiaode Zhang,
Nancy Olsen, and Song Guo Zheng. 2017. “Vitamin D and Chronic
Diseases.”Aging and Disease 8 (3): 346–53.


Aranow, Cynthia. 2011. “Vitamin D and the Immune System.” Journal
of Investigative Medicine: The Official Publication of the
American Federation for Clinical Research 59 (6): 881–86.


Li, Xinyi, Yan Liu, Yingdong Zheng, Peiyu Wang, and Yumei Zhang.
2018. “The Effect of Vitamin D Supplementation on Glycemic
Control in Type 2 Diabetes Patients: A Systematic Review and
Meta-Analysis.” Nutrients 10 (3).
https://doi.org/10.3390/nu10030375.


Pittas, Anastassios G., Bess Dawson-Hughes, Patricia Sheehan,
James H. Ware, William C. Knowler, Vanita R. Aroda, Irwin
Brodsky, et al. 2019. “Vitamin D Supplementation and Prevention
of Type 2 Diabetes.” The New England Journal of Medicine 381 (6):
520–30.


Kassi, Eva, Christos Adamopoulos, Efthimia K. Basdra, and
Athanasios G. Papavassiliou. 2013. “Role of Vitamin D in
Atherosclerosis.” Circulation 128 (23): 2517–31.


Al Mheid, Ibhar, and Arshed A. Quyyumi. 2017. “Vitamin D and
Cardiovascular Disease: Controversy Unresolved.” Journal of the
American College of Cardiology 70 (1): 89–100.


Yin, Lu, José M. Ordóñez-Mena, Tianhui Chen, Ben Schöttker,
Volker Arndt, and Hermann Brenner. 2013. “Circulating
25-Hydroxyvitamin D Serum Concentration and Total Cancer
Incidence and Mortality: A Systematic Review and Meta-Analysis.”
Preventive Medicine 57 (6): 753–64.


Han, Jianmin, Xiaofei Guo, Xiao Yu, Shuang Liu, Xinyue Cui, Bo
Zhang, and Hui Liang. 2019. “25-Hydroxyvitamin D and Total Cancer
Incidence and Mortality: A Meta-Analysis of Prospective Cohort
Studies.” Nutrients 11 (10). https://doi.org/10.3390/nu11102295.


Keum, N., and E. Giovannucci. 2014. “Vitamin D Supplements and
Cancer Incidence and Mortality: A Meta-Analysis.” British Journal
of Cancer 111 (5): 976–80.


Earthman, C. P., L. M. Beckman, K. Masodkar, and S. D. Sibley.
2012. “The Link between Obesity and Low Circulating
25-Hydroxyvitamin D Concentrations: Considerations and
Implications.” International Journal of Obesity 36 (3): 387–96.


Anglin, Rebecca E. S., Zainab Samaan, Stephen D. Walter, and
Sarah D. McDonald. 2013. “Vitamin D Deficiency and Depression in
Adults: Systematic Review and Meta-Analysis.” The British Journal
of Psychiatry: The Journal of Mental Science 202 (February):
100–107.


Hughes, D. A., and R. Norton. 2009. “Vitamin D and Respiratory
Health.” Clinical and Experimental Immunology 158 (1):
20–25.


Baktash, Vadir, Tom Hosack, Nishil Patel, Shital Shah,
Pirabakaran Kandiah, Koenraad Van den Abbeele, Amit K. J. Mandal,
and Constantinos G. Missouris. 2020. “Vitamin D Status and
Outcomes for Hospitalised Older Patients with COVID-19.”
Postgraduate Medical Journal, August.
https://doi.org/10.1136/postgradmedj-2020-138712.


Carpagnano, G. E., V. Di Lecce, V. N. Quaranta, A. Zito, E.
Buonamico, E. Capozza, A. Palumbo, G. Di Gioia, V. N. Valerio,
and O. Resta. 2021. “Vitamin D Deficiency as a Predictor of Poor
Prognosis in Patients with Acute Respiratory Failure due to
COVID-19.” Journal of Endocrinological Investigation 44 (4):
765–71.


Schwalfenberg, Gerry K. 2011. “A Review of the Critical Role of
Vitamin D in the Functioning of the Immune System and the
Clinical Implications of Vitamin D Deficiency.” Molecular
Nutrition & Food Research 55 (1): 96–108.